The common cannabinoid responsible for the psychoactive effects of cannabis, delta-9 tetrahydrocannabinol (THC), is well-known to most consumers. Exotic cannabinoids such as delta-8 and delta-10 are also well-known to many people. The use of these THC analogs is booming. However, because of the semi-synthetic qualities and psychoactive effects of delta-8 and delta-10, several states have recently outlawed them.
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Products from hemp companies are marketed as THCA flowers.
We go over THCA in this review, comparing it to THC and CBD and going over its advantages, applications, and product types.
What Is The THCA?
In hemp and cannabis (Cannabis sativa) plants, tetrahydrocannabinolic acid, or Delta-9 THCA, is a naturally occurring cannabinoid. It is found mostly in young, recently harvested cultivars and is the acidic?precursor? to THC. Until it undergoes non-enzymatic reactions with heat to produce THC, thca is not psychoactive. This process, called decarboxylation, is what gives cannabis its psychoactive effects.
Does THCA give users a high?
When taken in its natural form, THCA is not psychoactive. The way that THCA binds to brain receptors that are linked to inducing a high is due to its molecular structure. This is only applicable, though, when THCA is ingested unprocessed, as in the case of freshly harvested cannabis juice.
Comparing THCA and THC
Delta Nine While both THC and THCA are tetrahydrocannabinol compounds, there is a crucial molecular difference between them: THCA has a carboxylic acid group on a benzene ring, whereas THC does not. THCA has a larger molecular structure and a three-dimensional shape due to the additional ring, which prevents it from binding to neural receptors and producing psychoactive effects. THC is a liquid, but THCA is a crystalline solid due to its similar shape.
THCA loses the extra group during its conversion to THC, transforming into the well-known and euphoric substance.
Due to its distinct structure, THC can bind efficiently to CB1 and CB2 receptors, which are mainly found in the brain, central nervous system, and immune system. This neural affinity influences mental perception, leading to euphoric experiences, creative thought, and a buzzing sensation throughout the body.
Medicinal Effects of THCA
Many of THC’s medicinal properties are also shared by THCA. However, compared to THC, THCA interacts with the human body differently due to its additional carboxyl group. For instance, THCA and CBD, another well-known cannabinoid found in cannabis, exhibit certain effects more similarly.
Studies indicate that THCA may be useful for a variety of medical applications and health advantages, such as:
reduction of nausea and appetite in patients with cancer or eating disorders
lessening inflammation and pain
Mitigating long-term discomfort and spasms in the muscles, specifically related to Crohn’s disease, ulcerative colitis, and inflammatory bowel disease (IBD)
inhibiting the spread of cancer cells, particularly those in the prostate
Brain health includes things like preserving memory and motor function, preventing Huntington’s disease, and preventing other neuroinflammatory illnesses like ALS, Parkinson’s disease, and Alzheimer’s
relaxation, maybe as a treatment for insomnia and as a sleep aid
lessening epilepsy and multiple sclerosis patients’ seizures and spasms
FAQs regarding THCA
What are THCA’s advantages?
THCA protects the brain by exhibiting neuroprotective effects. Strong anti-inflammatory qualities, the ability to inhibit the growth of cancer cells, appetite stimulation, decreased nausea, and potential relief from seizure disorders are all present in this substance.
How is THCA not the same as CBD?
One more significant cannabinoid present in hemp and cannabis plants is CBD (cannabidiol). CBD and THCA are entirely different compounds in terms of structure. THCA and CBD are similar to each other in a few ways, though. Because neither THCA nor CBD binds well to the brain’s cannabinoid receptors, they are both non-psychoactive. They both provide advantages for seizure disorders and inflammation as well.
When smoked, does THCA turn into THC?
Sure. It takes a lot of heat from smoking to change most of the THCA in a product into regular THC.
How does the brain respond to THCA?
Unless it goes through decarboxylation, THCA does not bind to brain receptors similarly to THC. But THCA does show neuroprotective qualities that could be useful in treating and preventing diseases like Huntington’s, Parkinson’s, and Alzheimer’s.
